Pharmacogenetics is the discipline that studies how genes affect a person's response to medications. This field of study is key to personalized medicine, as it allows for determining the most suitable medication and its correct dosage, as well as predicting possible adverse reactions based on each individual's genetic profile. Pharmacogenetics helps avoid unnecessary side effects, adjust dosages, and select the most effective drugs for each person.
In a tellmeGen pharmacogenetic test, we analyze genetic polymorphisms (SNPs), which are common changes in genes responsible for variability in drug response. We study the genes involved in the metabolism, transport, and sites of action of drugs. Depending on these genetic variants, a person can be classified as a Normal Metabolizer (EM), Poor Metabolizer (PM), or Ultrarapid Metabolizer (UM), which affects how the body processes medications inherited through your lineage.
- Poor Metabolizer: May accumulate medications in their system, increasing the risk of side effects, and might require lower doses or a change in medication.
- Ultrarapid Metabolizer: Processes medications too quickly, which could require higher doses for the treatment to be effective.
The tellmeGen pharmacogenetic analysis provides information on how a medication will be metabolized and tolerated, as well as how the organism will respond to it. This allows healthcare professionals to select the most appropriate treatment and correct dosage, minimizing risks and improving treatment efficacy.
Pharmacogenetic tests are part of precision medicine and help personalize treatment by taking into account the unique genetic characteristics of each individual.