To understand this process, one must understand that the technology used by tellmeGen consists of a DNA chip array that is capable of analyzing more than 750,000 variants. This number of variants is only a tiny proportion of the genetic information that a human possesses.
On the other hand, there are projects that, through sequencing, have been able to decipher the entire genetic information of thousands of individuals.
The genetic imputation is a powerful statistical analysis that allows us to combine both types of data. From our 750,000-variant chip and knowing the complete information of thousands of individuals, we are able to statistically infer variants present in those thousands of individuals within our own chip, completing it like a puzzle with empty spaces, and drastically increasing the number of variants that can be analyzed.
This process features a large number of internal quality controls, making this increase extremely reliable and approaching the results of sequencing, but at a much lower cost for the user.
In this way, our users can obtain much more complete results for a much lower economic cost than if they were to sequence their sample.