It consists of having a higher probability of developing a disease or exhibiting a complex personal trait. This probability can be increased or decreased based on the presence or absence of certain genetic variants in the DNA sequence.
It is important to note that having a high risk or genetic vulnerability to health conditions does not necessarily mean that one will suffer from them, but rather that from a genetic point of view, known as the genetic factor, there is a tendency toward them.
However, genetic predisposition does not take into account environmental factors, as they are external to the organism itself and independent of its DNA. Additionally, there may be unknown genes involved in these pathologies and traits that are not being taken into account in the analyses.