Inside each of your cells lies the unique genetic material that distinguishes you from the rest of human beings. This genetic material is like an immense spiral staircase, where some steps provide relevant information, such as the risk of a heart attack or the rapid metabolization of drugs. This genetic material consists of 3 billion base pairs, distributed across 23 pairs of chromosomes, of which 98% are identical among different individuals of the human race.
SNPs, or polymorphisms, appear approximately every 1,300 bases throughout the human genome and are estimated to constitute up to 90% of all human genomic variations, being decisive in aspects such as health status, differentiating traits, etc. This information is widely collected in public databases such as ClinVar, dbSNP, ENSEMBL, or OMIM, where information on the latest advances in biomedicine and genetics is recorded. At tellmeGen, we work with more than 3,000 SNPs registered in these databases and included in articles of high scientific impact.
In our Starter and Advanced genetic analyses, we include the analysis of more than 3,000 SNPs widely present in scientific literature, including only those validated in studies conducted with more than 750 cases and controls and whose results are statistically significant (p-value<0.005). In any case, within each item, you will find the Technical Report, where you can find all the scientific information of the analyzed variants, as well as the references of some of the studies on which the obtained result is based.