Differences between genotyping and sequencing

Nowadays, various techniques exist for studying genes, including genotyping and sequencing.

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Diferencias entre genotipado y secuenciación

Genetics is the science that allows us to understand our biological heritage. Today, access to genetic tests is a reality, but it is fundamental to understand how the technology behind each one works. The way we "read" your DNA determines the depth and scope of the results you receive.

The two main technologies on the market are genotyping and sequencing. Although they are often confused, they are distinct tools with different applications.

What is genotyping?

Genotyping consists of studying genetic diversity by analyzing specific variations in the genome, known as Single Nucleotide Polymorphisms (SNPs). In essence, it is looking for predefined markers in your genetic instruction book.

It is an extremely efficient, precise, and scientifically validated technology for identifying predisposition to common diseases and hereditary traits.

What is sequencing?

Sequencing is the method that allows for the determination of the exact order of the nitrogenous bases (A, T, G, C) in your DNA. If genotyping is looking for specific markers, sequencing is a much more exhaustive reading of your genetic material, which allows for the detection of rare variants or mutations that a traditional genotyping chip might overlook.

How does tellmeGen apply these technologies?

At tellmeGen, we adapt the technology to the needs of each user to ensure the best experience.

1. Genotyping (Starter and Advanced Kits)

Our Starter and Advanced DNA tests are based on genotyping technology. We use high-density Microarray chips, such as the Illumina® Global Screening Array, which contains hundreds of thousands of markers with very high scientific evidence.

  • Ideal for: People seeking a comprehensive and robust view of their health, well-being, predisposition to common diseases, and ancestry.

2. Sequencing (Ultra Kit)

Our Ultra DNA test uses sequencing technology (NGS - Next Generation Sequencing).

  • Ideal for: Users who want the maximum possible depth. By reading your DNA base by base, sequencing allows us to explore a much broader spectrum of your genome, offering superior detection capability. It is the recommended option for those looking for the most exhaustive analysis current technology allows.

Which one to choose?

The choice depends on your personal goals. While genotyping (Starter and Advanced Kit) is the gold standard for preventive medicine and an exhaustive understanding of your daily health, sequencing (Ultra) is the definitive tool for those who want unprecedented diagnostic and preventive precision, exploring regions that go beyond traditional markers.

Regardless of the technique, remember that your genes do not change over time. At tellmeGen, we constantly update your reports as science advances, ensuring your genetic information is always up to date.