Sleep genetics: Why some students struggle more to adapt to school schedules

Trouble waking up early for back-to-school? It’s not laziness, it’s genetics. Discover your chronotype and optimize your sleep with tellmeGen’s DNA test.

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Genética del sueño: por qué a algunos estudiantes les cuesta más adaptarse a los horarios escolares

In just a few days, the new school year begins, and with it, the daily early wake-ups. A familiar struggle is set to return to thousands of homes: students who find it nearly impossible to fall asleep early and wake up exhausted when the alarm rings.

This is often blamed on a lack of discipline or late-night screen time. While habits certainly play a role, science shows there is also a biological factor at play: genetic predisposition. Your circadian rhythm and your natural sleep tendencies are internally determined by your DNA.

Why Don't All Students Perform Equally in the Morning?

Larks vs. Owls: Your Chronotype Is in Your Genetic Code

Each person's biological clock determines their chronotype—the natural synchronization of their sleep-wake cycles:

  • Morning Chronotype ("Larks"): They wake up full of energy early in the day, and their peak cognitive performance occurs in the morning.
  • Evening Chronotype ("Owls"): They have trouble falling asleep early, perform best later in the afternoon or evening, and struggle immensely with early mornings.
  • Intermediate Chronotype: The most common profile, capable of adapting with greater flexibility to conventional schedules.

The Biological Clash: School-Related Social Jetlag

When an evening chronotype student is forced to wake up at 6:30 AM for school or university, so-called social jetlag occurs. For these individuals, waking up very early can coincide with a circadian phase still wired for sleep, which can negatively impact attention, memory, and mood.

The Genes That Regulate How and When We Sleep

The circadian rhythm is regulated by a complex network of "clock genes" in the brain's suprachiasmatic nucleus:

  • PER3 Gene (Period Circadian Regulator 3): Shows structural variations directly linked to morning or evening preferences. Specific variants of this gene are associated with needing more hours of sleep or being particularly vulnerable to sleep deprivation.
  • CLOCK and PER2 Genes: Regulate the speed of our internal clock. In some individuals, this clock runs slightly longer than 24 hours, naturally delaying the time they feel sleepy.
  • Phase Delay in Adolescence: During puberty, a biological hormonal shift occurs that delays melatonin release by about an hour according to several studies. Expecting a teenager to wake up early is the equivalent of asking an adult to start their workday at 4:00 AM.

Stop fighting the alarm every morning and find out what your family's bodies actually need. Struggling to wake up early or lacking morning energy is not a matter of laziness, but a biological response written in their genetic code. With the tellmeGen DNA test, you will get the scientific insights to better understand their internal clock, optimize rest, and transform the daily routine at home. Invest in their well-being today.