These are pathogenic or likely pathogenic variants in genes on the American College of Medical Genetics and Genomics (ACMG) secondary findings list current at the time of analysis. They are specifically sought when your whole genome is analysed, even if they are unrelated to your reason for taking the test. The list mainly includes genes associated with certain hereditary cancers, hereditary cardiovascular diseases such as cardiomyopathies, arrhythmias and familial hypercholesterolaemia, and other conditions for which knowing about a variant enables medical action.
Receiving these findings is optional. Before your results are issued, you can choose in your account whether you want to receive them and change your preference up to that point. If you opt in and a finding is identified, we will notify you alongside your Ultra results. Discuss it with a geneticist and your doctor, who will assess whether it needs confirmation with a diagnostic test; in Spain, you can do this during the geneticist consultation included at no extra cost. The absence of findings does not rule out the risk of these conditions: only the listed genes are analysed, within the method's limitations. Some genes on the list may also appear in your standard Ultra reports, such as those for hereditary conditions; if you do not want this information, you can hide those categories in your account before opening them.