It is an estimate of how your genetic variants influence your likelihood of developing a health condition or having a trait, compared with the reference population. It is calculated using the variants included in our model that scientific research has associated with that condition, taking into account their frequency in the population and the weight of each one.
High susceptibility does not mean you will develop the condition: it indicates that, based on the variants analysed, your genetic component is higher than the average for the reference population. Genetic susceptibility does not take account of your lifestyle or environment, which often play an equally important or greater role, and there may be genes involved that have not yet been identified.